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KMID : 1001920170600010094
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Journal of Korean Neurosurgical Society
2017 Volume.60 No. 1 p.94 ~ p.97
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Skull Metastasis of Gastric Gastrointestinal Stromal Tumor Successfully Managed by Surgery
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Park In-Keun
Chung Dong-Hae
Yoo Chan-Jong
Shin Dong-Bok
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Abstract
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Gastrointestinal stromal tumors (GISTs) are rare, but are the most common mesenchymal neoplasm of the gastrointestinal tract. The most common sites of metastasis are liver and peritoneum, while bone metastasis is rare. We report on a patient with skull metastasis after seven years of treatment with imatinib for metastatic GIST. She underwent metastasectomy consisting of craniectomy with excision of the mass, and cranioplasty and continued treatment with imatinib and sunitinib, without evidence of cranial recurrence. She died of pneumonia sepsis one year after metastasectomy. Skull metastasis of GIST is a very rare presentation, and an aggressive multidisciplinary approach should be considered whenever possible.
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KEYWORD
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Gastrointestinal stromal tumor , Skull metastasis , Metastasectomy , Target therapy , Multidisciplinary treatment
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